Search on: 2,5 OLIGOADENYLATE POLYMERASE 
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Descriptor English:   2',5'-Oligoadenylate Synthetase 
Descriptor Spanish:   2',5'-Oligoadenilato Sintetasa 
Descriptor Portuguese:   2',5'-Oligoadenilato Sintetase 
Synonyms English:   (2'-5')An Polymerase
2',5' Oligoadenylate Polymerase
2',5' Oligoadenylate Synthetase
2',5'-Oligo(A) Polymerase
2',5'-Oligo(A) Synthetase
2',5'-Oligoadenylate Polymerase
2,5 Oligoadenylate Polymerase
2,5 Oligoadenylate Synthetase
2-5A Synthetase
ATP-(2'-5')oligo(A)adenylyltransferase
Oligoadenylate Polymerase, 2,5
Oligoadenylate Synthetase, 2,5
Polymerase, 2',5'-Oligoadenylate
Polymerase, 2,5 Oligoadenylate
Synthetase, 2',5'-Oligoadenylate
Synthetase, 2,5 Oligoadenylate  
Tree Number:   D08.811.913.696.445.625
Definition English:   An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions. 
History Note English:   83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   21042 
Unique Identifier:   D015088 

Occurrence in VHL: 		 

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DeCS